Trabectedin
Checked 2026-09-09
Liposarcoma and leiomyosarcoma after an anthracycline
One cycle
every 21 daysComponents
| Drug | Dose | Route | Days | Note |
|---|---|---|---|---|
Trabectedin Cytotoxic (DNA minor-groove binder) | 1.5 mg/m² through a central line | IV | D1 (24 h infusion) |
Cycles
until progression
21-day cycle
Emetogenicity
Moderate (30-90%)
G-CSF
Not routine
Notes
- Dexamethasone 20 mg IV 30 minutes before each dose reduces hepatotoxicity.
Used in
Products
Source
Reference doses for a typical adult from the cited protocol or label. Doses are adjusted for renal and hepatic function, age, performance status and prior toxicity, and institutional protocols vary. Verify against the current label and your local protocol before treating. Not medical advice.