Carcinoma in situ and dysplasia of the gallbladder: lines of therapy
3 standard-of-care settings across 1 lines and 1 biomarker subgroup. Rows come from the cancer page's standard of care; the grid places each on its line and subgroup.
| Line | All comers |
|---|---|
| Other settings | 3 |
Other settings
| Subgroup | Setting | Approach | Products and trials | Guideline | Evidence |
|---|---|---|---|---|---|
| All comers | Tis or dysplasia with a clear cystic duct margin | No further surgery; follow-up because occasional late recurrences reflect a field effect. | - | ||
| All comers | Positive cystic duct margin or Rokitansky-Aschoff sinus involvement | Consider bile duct margin re-excision or further surgery at a hepatobiliary centre. | - | ||
| All comers | Gallbladder polyp in primary sclerosing cholangitis | Cholecystectomy advised for polyps of any size by international guidelines; a 2020 cohort supports short-interval imaging first when no high-risk feature is present. | - |
Lines and subgroups are parsed from the setting text of each standard-of-care row and can misclassify an unusual phrasing; the row’s own setting is always shown. Guideline chips reflect the NCCN category and ESMO-MCBS grade recorded on the cancer page, checked on its stated date. Not medical advice.