Pleuropulmonary blastoma (types I, Ir, II and III): lines of therapy

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2 standard-of-care settings across 1 lines and 1 biomarker subgroup. Rows come from the cancer page's standard of care; the grid places each on its line and subgroup.

Line	All comers
Other settings	2

Other settings

Subgroup	Setting	Approach	Products and trials	Guideline	Evidence
All comers	Type I and Ir	Complete resection of the cyst; chemotherapy debated; DICER1 testing and surveillance.	Childhood lung and airway tumours (pleuropulmonary blastoma, tracheobronchial tumours)Germline (hereditary) testing		94
All comers	Type II and III	Resection and multi-agent chemotherapy (ifosfamide, vincristine, actinomycin, doxorubicin), radiotherapy for residual disease.	IfosfamideVincristineDoxorubicinChildhood lung and airway tumours (pleuropulmonary blastoma, tracheobronchial tumours)		79

Lines and subgroups are parsed from the setting text of each standard-of-care row and can misclassify an unusual phrasing; the row’s own setting is always shown. Guideline chips reflect the NCCN category and ESMO-MCBS grade recorded on the cancer page, checked on its stated date. Not medical advice.