Solid pseudopapillary neoplasm of the pancreas: lines of therapy

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2 standard-of-care settings across 2 lines and 1 biomarker subgroup. Rows come from the cancer page's standard of care; the grid places each on its line and subgroup.

Line	All comers
Early / localised	1
Advanced, first line	1

Early / localised

Subgroup	Setting	Approach	Products and trials	Guideline	Evidence
All comers	Localised	Complete resection: distal pancreatectomy for body and tail tumours, pancreatoduodenectomy for the head, parenchyma-sparing surgery considered in young patients; no adjuvant therapy; long-term follow-up imaging for late recurrence.	Distal pancreatectomy (removal of the body and tail of the pancreas, usually with the spleen)Whipple procedure (pancreaticoduodenectomy)Robotic & minimally invasive surgeryMRI	NCCN Guidelines: Pancreatic Adenocarcinoma	40

Advanced, first line

Subgroup	Setting	Approach	Products and trials	Guideline	Evidence
All comers	Recurrent or metastatic	Resection of recurrences and liver metastases where feasible; no established systemic therapy; case reports only.	Oligometastatic diseaseDistal pancreatectomy (removal of the body and tail of the pancreas, usually with the spleen)	NCCN Guidelines: Pancreatic Adenocarcinoma	-

Lines and subgroups are parsed from the setting text of each standard-of-care row and can misclassify an unusual phrasing; the row’s own setting is always shown. Guideline chips reflect the NCCN category and ESMO-MCBS grade recorded on the cancer page, checked on its stated date. Not medical advice.