t-cell-engager-target
No description yet: the sentence for this tag has not been written. 6 records carry it: 6 targets.
Related tags
6 records
| Cancers | Other tags | ||||
|---|---|---|---|---|---|
BCMA TNFRSF17 BCMA is a survival receptor on plasma cells, and the target that made CAR-T and bispecifics work in multiple myeloma. | Multiple myeloma | none | car-t-target | ||
CD3 CD3E CD3 is the switch on every T cell. Bispecific drugs grab it with one arm and the tumour with the other, forcing the T cell to attack. | none | none | none | ||
DLL3 DLL3 A protein that appears on the surface of small-cell lung cancer cells, now hit by a drug that pulls T cells onto them. | Small-cell lung cancer, Prostate cancer | none | none | ||
| Multiple myeloma | none | none | |||
KLK2 (kallikrein-2) KLK2 A relative of PSA that stays attached to prostate cancer cells, used as a T-cell engager address by J&J. | Prostate cancer | none | none | ||
STEAP1 STEAP1 STEAP1 is a protein on the surface of most prostate cancer cells, now the address for a T-cell engager in phase 3. | Prostate cancer | none | none |