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Every dated change on the records linked to Breast implant-associated anaplastic large cell lymphoma, newest first: approvals and regulatory steps on its medicines, trials that reported, guideline versions, milestones, and when this page itself was checked. Dates come from the records; none is inferred. Orientation, not medical advice.
A seroma appearing around a breast implant more than a year after the operation is aspirated and the fluid sent for cytology and for CD30 immunohistochemistry, rather than simply drained. That single step is what makes the diagnosis, and draining without testing is how it is missed. The same applies to a new mass in the capsule or to capsular contracture appearing years after surgery. Imaging, usually ultrasound in the first instance, maps the fluid and any mass.
WHO-HAEM5 lists it as one of the three anaplastic large cell lymphomas, describes it as usually non-invasive and associated with an excellent outcome, and records that invasion of adjacent structures worsens the outlook.