Localised anal squamous cell carcinoma (stage I to III)

What changed: Localised anal squamous cell carcinoma (stage I to III)

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Every dated change on the records linked to Localised anal squamous cell carcinoma (stage I to III), newest first: approvals and regulatory steps on its medicines, trials that reported, guideline versions, milestones, and when this page itself was checked. Dates come from the records; none is inferred. Orientation, not medical advice.

Trial result1Milestone6This record1

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September 2026 · 1

2026-09-18This recordLocalised anal squamous cell carcinoma (stage I to III)
Facts on this page last checked
When this page itself was last checked or edited.

2019 · 1

2019MilestoneIMRT / IGRT (modern external beam)
PLATO trials open to personalise radiotherapy dose by stage
A milestone in how this cancer is treated.

2016 · 1

2016MilestoneIMRT / IGRT (modern external beam)
Intensity-modulated radiotherapy becomes standard after RTOG 0529 reduces toxicity
A milestone in how this cancer is treated.

2013 · 2

2008 · 1

2008MilestoneMitomycin C
RTOG 98-11: mitomycin-based chemoradiotherapy beats induction cisplatin
A milestone in how this cancer is treated.

1996 · 1

1996MilestoneChemoradiation (chemoradiotherapy, CRT)
UKCCCR ACT I: chemoradiotherapy beats radiotherapy alone
A milestone in how this cancer is treated.

1974 · 1

1974MilestoneFluorouracil (5-FU)
Nigro reports complete responses to fluorouracil, mitomycin and radiotherapy, sparing the anus
A milestone in how this cancer is treated.