What changed: MET exon 14 and MET-amplified non-small-cell lung cancer
Every dated change on the records linked to MET exon 14 and MET-amplified non-small-cell lung cancer, newest first: approvals and regulatory steps on its medicines, trials that reported, guideline versions, milestones, and when this page itself was checked. Dates come from the records; none is inferred. Orientation, not medical advice.
Regulatory1Trial result2Milestone5This record1
September 2026 · 1
2025 · 1
2024 · 2
January 2022 · 1
2021 · 1
2020 · 2
- 2020Trial resultGEOMETRY mono-1GEOMETRY mono-1 reported
Response rate 68% (treatment-naive, n=28) and 41% (previously treated, n=69) in MET exon 14 skipping disease; about a third in high-level MET amplification.
- 2020MilestoneGEOMETRY mono-1GEOMETRY mono-1: capmatinib approved; VISION: tepotinib reported
A milestone in how this cancer is treated.