What changed: Wilms tumour (nephroblastoma)
Every dated change on the records linked to Wilms tumour (nephroblastoma), newest first: approvals and regulatory steps on its medicines, trials that reported, guideline versions, milestones, and when this page itself was checked. Dates come from the records; none is inferred. Orientation, not medical advice.
Approval2Trial result2Guideline2Milestone7This record1
September 2026 · 1
2019 · 2
- 2019GuidelineWilms tumour (nephroblastoma)Guideline COG AREN0532 (JCO 2019): Very low risk (stage I FH, <2 years, <550 g)
Nephrectomy alone with close surveillance (AREN0532).
- 2019MilestoneActive surveillanceAREN0532: surgery alone confirmed for very-low-risk stage I
A milestone in how this cancer is treated.
2018 · 3
- 2018GuidelineWilms tumour (nephroblastoma)Guideline COG AREN0533 (JCO 2018): Stage III-IV favourable histology
Vincristine, actinomycin D, doxorubicin (DD-4A) for 24 weeks; flank/abdominal radiotherapy for stage III; whole-lung radiotherapy for lung metastases not in rapid complete response (AREN0533).
- 2018Trial resultCOG AREN0533COG AREN0533 reported
Overall 4-year EFS 85.
- 2018MilestoneIMRT / IGRT (modern external beam)AREN0533: lung radiotherapy omitted for rapid complete responders
A milestone in how this cancer is treated.