companiesCompany
CRISPR Therapeutics
aka CRISPR Therapeutics AG, NASDAQ:CRSP
CRISPR Therapeutics is the gene-editing company co-founded by Emmanuelle Charpentier that shares Casgevy with Vertex and is building off-the-shelf CAR-T cells such as CTX112 for lymphoma and autoimmune disease.
Overview
CRISPR Therapeutics, headquartered in Zug with research in Boston, uses CRISPR/Cas9 to make gene-edited medicines. With Vertex it brought exagamglogene autotemcel (Casgevy) to approval for sickle cell disease and beta thalassaemia. In oncology it develops allogeneic CAR-T cells made from healthy donor T cells: CTX112 targets CD19 in B-cell malignancies and lupus, and CTX131 targets CD70 in solid tumours and haematological cancers. The company also has in vivo editing programmes for cardiovascular disease.
Headquarters
Zug, CH
Scorecard
All companies#377of 1181 companies, score 8
- phase 1/2 +1
- targets +2
- modalities +2
- registry trials +3
0 approved, 0 in phase 3, 1 earlier, 1 targets, 3 registry studies. Formula on the scorecards page.
Type
cell therapy · NASDAQ:CRSP
Stage
Public
Website
Founded
2013