GV20 Therapeutics
GV20 Therapeutics is a US-based biotechnology company that leads 2 cancer trials in OnCo, testing the anti-IGSF8 antibody GV20-0251 in endometrial cancer, head and neck squamous cell carcinoma, melanoma and non-small-cell lung cancer.
Overview
GV20 Therapeutics is a clinical-stage biotechnology company that uses its AI-driven STEAD platform, combining B-cell repertoire data, omics data and disease biology, to discover antibody targets and therapeutics. Its lead candidate GV20-0251 is a first-in-class antibody against the immune checkpoint IGSF8, in phase 1 in the United States and China. On ClinicalTrials.gov it is the lead sponsor of 2 trials recorded in OnCo: NCT05669430 (phase 1/2, A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Par...) and NCT07070518 (phase 1/2, Study of GV20-0251 in Participants With Solid Tumor Malignancies). Sponsor and trial facts are from the ClinicalTrials.gov registry; company facts are from the official website.
Scorecard
All companies- approved products +6
- targets +2
- modalities +2
- regions +6
- 24-month regulatory events +6
- registry trials +30
Similar pages
not linked directly; found by shared links- TrialA Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
Shares Endometrial cancer, Head and neck squamous cell carcinoma, Non-small-cell lung cancer.
- TrialA Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2
Shares Endometrial cancer, Head and neck squamous cell carcinoma, Non-small-cell lung cancer.
- TrialA Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Shares Endometrial cancer, Melanoma, Non-small-cell lung cancer.
- TrialAn Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors
Shares Endometrial cancer, Melanoma, Non-small-cell lung cancer.
- TrialA Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
Shares Endometrial cancer, Small-cell lung cancer, Non-small-cell lung cancer.
- PairingPD-1 blockade + VEGF inhibition
Shares Endometrial cancer, Hepatocellular carcinoma, Pembrolizumab, Non-small-cell lung cancer.
- PersonJean-Pierre Delord
Shares Endometrial cancer, Head and neck squamous cell carcinoma.
- TrialPsilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder
Shares Endometrial cancer, Melanoma.