Kibur Medical makes a tiny implant that releases small doses of up to 20 cancer drugs into different spots of a tumour at once, so researchers can see which drugs or combinations work on that tumour. It sells this mainly to companies developing cancer drugs.
Kibur Medical describes a tumour-implanted, drug-eluting device it calls the NanoNail, which releases up to 20 individual oncology drugs or drug combinations into a tumour at the same time. After the device and surrounding tissue are retrieved, the company analyses multi-omic, spatially registered single-cell data with machine learning to measure how the tumour responded to each drug. It offers this to drug developers for choosing combinations, lead compounds, mechanism of action and predictive biomarkers, in animal models and in human tumours, and names a partnership with Charles River. The site highlights published work including an implantable microdevice study in breast cancer models (Nature Biotechnology 2022) and a study of intratumoral drug-releasing microdevices in patients with high-grade gliomas. Third Rock Ventures lists Kibur under Cancer and Device and Therapeutic Technology, with 2012 as its year of investment.
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