A tumour board assistant that cites its evidence and tracks outcomes
Give every tumour board a tool that pulls up the relevant trials and guideline lines for each case with citations, records what was decided, and later shows how the patient did.
Molecular tumour boards spend much of their time on literature search and produce recommendations that are rarely tracked to outcomes. The proposal is an assistant built on the evidence graph and computable guidelines: it prepares a cited evidence brief per case, records the board's recommendation in structured form, and links it to the patient's subsequent treatment and outcome, creating a learning loop across boards. Precedents include MSK's OncoKB-driven annotation and academic MTB decision-support pilots.
- Knowledge reaches practice too slowly · Knowledge diffusion is slow: it takes years for a proven result to change what most patients receive, and no one can keep up with the literature.
- Weak real-world evidence and registries · We do not reliably know what happens to patients after approval, so we cannot tell which drugs deliver in practice.
Pages like this
not linked directly; found by shared links- IdeaAn open knowledge graph linking trials, results, biomarkers, drugs and recommendations
Shares Decision support that cites the exact trial and guideline line it relies on, OncoKB, Knowledge reaches practice too slowly.
- IdeaLabel every biomarker claim with an evidence phase, like drugs
- IdeaA public tracker of how long each country takes to adopt new evidence
Shares Weak real-world evidence and registries, Knowledge reaches practice too slowly.
- TechnologyCancer variant knowledgebases and molecular tumour boards
- IdeaA real-world sequencing analysis within a year of every new approval
Shares Weak real-world evidence and registries, Knowledge reaches practice too slowly.
- IdeaEvery tumour sequencing report lists open, nearby, matched trials pulled live
- IdeaEvery tumour genomic report machine-readable and deposited nationally
- IdeaLiving guidelines published as versioned, computable rules
Shares Decision support that cites the exact trial and guideline line it relies on, Knowledge reaches practice too slowly.