Blood-based pancreatic cancer detection in new-onset diabetes
Adults who suddenly develop diabetes after 50 have several times the usual risk of pancreatic cancer. Test their blood.
About 1% of new-onset diabetes after age 50 is caused by an occult pancreatic cancer (~6-8x relative risk in the first 3 years). The END-PAC risk model and the NCI New Onset Diabetes (NOD) cohort define a testable population; MCED, CA19-9 variants, and AI-read CT are candidate tests.
Pages like this
not linked directly; found by shared links- IdeaMulti-cancer blood test as the first step for patients with non-specific symptoms
Shares Galleri, Positive predictive value (PPV), Multi-cancer early detection (MCED), Most lethal cancers are found late.
- CompanyHarbinger Health
Shares Positive predictive value (PPV), Multi-cancer early detection (MCED), Most lethal cancers are found late.
- InstitutionFred & Pamela Buffett Cancer Center
Shares High-risk pancreatic surveillance (CAPS / PRECEDE), Most lethal cancers are found late, Pancreatic ductal adenocarcinoma.
- TrialPATHFINDER 2
Shares Galleri, Positive predictive value (PPV), Multi-cancer early detection (MCED), Most lethal cancers are found late.
- IdeaFAPI PET as the workup for MCED positives
Shares Galleri, Multi-cancer early detection (MCED), Most lethal cancers are found late, Pancreatic ductal adenocarcinoma.
- IdeaA whole-population cancer interception programme: risk-stratify every adult, detect and intercept early
Shares Galleri, Positive predictive value (PPV), Multi-cancer early detection (MCED), Most lethal cancers are found late.
- IdeaA breath test to rule out cancer in people with vague symptoms
Shares Positive predictive value (PPV), Most lethal cancers are found late.
- Key paperNHS-Galleri: design of the largest randomised trial of a multi-cancer blood test
Shares Galleri, Positive predictive value (PPV), Multi-cancer early detection (MCED), Most lethal cancers are found late.