Trial-in-a-box: a preconfigured protocol kit any hospital can open for a rare cancer
For rare cancers, the patient is often at a hospital that has no trial. A ready-made kit with the protocol, consent forms, database and shipping already set up would let that hospital enrol them within days.
A cooperative group or rare-cancer consortium maintains modular, pre-approved protocol packages for rare histologies: template protocol with pre-negotiated ethics approval under a central IRB, eConsent, cloud EDC, sample-shipping kits and a remote investigator-of-record model where local clinicians act as sub-investigators. Combined with just-in-time activation, the kit lets any accredited hospital enrol its one patient.
- Trials enrol too few, too slowly · Fewer than one in ten adults with cancer joins a trial. Trials close for lack of patients, not lack of ideas.
- Rare and paediatric cancers without markets · Taken together rare cancers are a fifth of all cancers, but each one alone is too small for a company to invest in.
Pages like this
not linked directly; found by shared links- IdeaOne global rare cancer network with n-of-1 and Bayesian trial frameworks
Shares EORTC, Basket, umbrella, and platform trials, Mesothelioma, Biliary tract cancer (cholangiocarcinoma).
- IdeaOne standing umbrella trial for all rare cancers in a country
Shares Basket, umbrella, and platform trials, Trials enrol too few, too slowly, Biliary tract cancer (cholangiocarcinoma), Neuroendocrine tumours.
- IdeaOne legal framework for pooling rare cancer data across borders
Shares Mesothelioma, Rare and paediatric cancers without markets, Sarcomas (soft tissue, bone, GIST).
- IdeaMandatory national virtual tumour boards for rare and complex cancers
Shares Neuroendocrine tumours, Rare and paediatric cancers without markets, Sarcomas (soft tissue, bone, GIST).
- IdeaJust-in-time site activation: open a site in two weeks when a patient appears
Shares Basket, umbrella, and platform trials, Trials enrol too few, too slowly, Rare and paediatric cancers without markets.
- IdeaAn open model bank for the rare tumours nobody has models for
Shares Mesothelioma, Biliary tract cancer (cholangiocarcinoma), Neuroendocrine tumours, Rare and paediatric cancers without markets.
- IdeaA funded expert second opinion for every new high-stakes or rare cancer diagnosis
Shares Neuroendocrine tumours, Rare and paediatric cancers without markets, Sarcomas (soft tissue, bone, GIST).
- IdeaThe pathology lab triggers a trial referral the day a rare cancer is diagnosed
Shares Trials enrol too few, too slowly, Neuroendocrine tumours, Rare and paediatric cancers without markets, Sarcomas (soft tissue, bone, GIST).