Time-stamped electronic lab notebooks submitted with the paper
Electronic notebooks record when each experiment was done and what the raw result was. Submitting them with the paper would show whether the analysis was planned or fitted after the fact.
Electronic lab notebooks are widespread but their audit trails are never shared. Submitting a cryptographically time-stamped export of the relevant notebook entries (or hashes anchored to a public ledger at the time of the experiment) with a manuscript would let reviewers verify the sequence of hypotheses, experiments and analyses, and would deter post hoc rationalisation.
- Preclinical results do not reproduce · Fewer than half of landmark cancer biology findings reproduce when someone else tries.
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not linked directly; found by shared links- IdeaPre-register biomarker validation studies the way trials are registered
Shares Registered reports for cancer biology: the plan is peer-reviewed before the result, Preclinical results do not reproduce.
- IdeaRandom audits of published, funded research, like tax audits
Shares Deposit the raw blots, gels and microscopy images behind every figure, Preclinical results do not reproduce.
- IdeaJournals check that data links actually work, and flag papers whose data vanish
Shares Deposit the raw blots, gels and microscopy images behind every figure, Preclinical results do not reproduce.
- IdeaRun automated statistics and image checks on every cancer manuscript before review
Shares Deposit the raw blots, gels and microscopy images behind every figure, Preclinical results do not reproduce.