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A public neurological hospital and research institute in Milan. It treats brain and spinal cord tumours in adults and children, with surgeons, brain tumour doctors, pathologists and radiotherapists working as one team.
The Fondazione IRCCS Istituto Neurologico Carlo Besta is a public, single-specialty Istituto di Ricovero e Cura a Carattere Scientifico for the neurosciences. It was founded in 1918, classified as an IRCCS from 1981 and became a Fondazione IRCCS in 2006; its founding members are the Lombardy region, the Ministry of Health and the City of Milan. Its functional neuro-oncology department (DIFNO) brings together clinical neuro-oncology, neuropathology, neurosurgery, neuroradiology and radiotherapy, holds multidisciplinary meetings for adult and paediatric cases, offers access to trials including phase 1, and takes part in the glioblastoma working group of Alleanza Contro il Cancro on liquid biopsy in brain tumours. Units listed include oncological neurosurgery (Neurochirurgia 1), neuro-oncology (Neurologia 2), brain metastasis surgery, paediatric neurosurgery, oncological neuropathology, experimental neuro-oncology, brain tumour immunotherapy and radiotherapy. The oncological neurosurgery unit describes intraoperative MRI, neuronavigation, fluorescence guidance, laser interstitial thermal therapy and robot-assisted biopsy, an internal tumour board, and trials in glioblastoma and focused ultrasound to open the blood-brain barrier.
Newsweek and Statista rank it 149th in World's Best Specialized Hospitals 2026: Oncology.
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