Innovative Therapies for Children with Cancer (ITCC)
Europe's network of children's hospitals that run the first trials of new cancer drugs in children, so that European children can access experimental medicines close to home.
Overview
Founded in 2003 and coordinated from Gustave Roussy, ITCC links more than 60 European paediatric oncology centres and around 25 research laboratories to conduct early-phase (phase 1 and 2) trials of new anticancer agents in children and adolescents. It runs academic platform trials including ESMART (molecularly matched combinations at relapse, the European counterpart of Pediatric MATCH) and the MAPPYACTS sequencing programme, partners with industry on paediatric investigation plans, and works with SIOP Europe and ACCELERATE on regulatory strategy. ITCC-P4 built a library of paediatric patient-derived xenograft models for preclinical testing under the IMI programme.
- Early-phase paediatric trials network
- ESMART platform trial
- MAPPYACTS molecular profiling
- ITCC-P4 preclinical PDX platform
- Industry partnerships for paediatric investigation plans
Pages like this
not linked directly; found by shared links- InstitutionHistiocyte Society
Shares Rare and paediatric cancers without markets and the tags nci-coverage, paediatric.
- TrialACTION
Shares RACE for Children Act, Diffuse midline glioma, H3 K27-altered (including DIPG), Rare and paediatric cancers without markets and the tags nci-coverage, paediatric.
- CancerRare cancers of childhood (NCI PDQ umbrella)
Shares NCI-COG Pediatric MATCH (APEC1621), RACE for Children Act, SIOP Europe – European Society for Paediatric Oncology, Trials enrol too few, too slowly and the tags nci-coverage, paediatric.
- CancerEpendymoma
Shares NCI-COG Pediatric MATCH (APEC1621), SIOP Europe – European Society for Paediatric Oncology, Paediatric low-grade glioma, Rare and paediatric cancers without markets and the tags nci-coverage, paediatric.
- TrialFIREFLY-1
Shares RACE for Children Act, Paediatric low-grade glioma and the tags nci-coverage, paediatric.
- TrialTADPOLE (CDRB436G2201)
Shares RACE for Children Act, Paediatric low-grade glioma and the tags nci-coverage, paediatric.
- CancerChildhood lung and airway tumours (pleuropulmonary blastoma, tracheobronchial tumours)
Shares SIOP Europe – European Society for Paediatric Oncology, Rhabdomyosarcoma, Rare and paediatric cancers without markets and the tags nci-coverage, paediatric.
- TrialInter-B-NHL Ritux 2010
Shares SIOP Europe – European Society for Paediatric Oncology, Gustave Roussy and the tags nci-coverage, paediatric.