8th Edition of the AJCC Cancer Staging Manual: Pancreas and Hepatobiliary Cancers
The editorial announcing the 2017 staging changes for pancreas, liver and biliary cancers, including the split of muscle-invading gallbladder cancer into a free-side and a liver-side category.
Overview
Editorial in Annals of Surgical Oncology by AJCC hepatobiliary panel members introducing the eighth edition changes. Europe PMC indexes no abstract for this article, so OnCo carries no figures from it. For gallbladder cancer the edition subdivided T2 into T2a (peritoneal side) and T2b (hepatic side), following the Shindoh 2015 multicentre study, and reclassified N stage by the number of positive nodes rather than their location (as the validation study linked here describes).
- No abstract is indexed on Europe PMC; the T2a/T2b subdivision is documented in the validation and meta-analysis papers linked from this record.
The staging change UK pathology reports now carry. Validation against the US National Cancer Database (Giannis 2021) found the eighth edition no better than the seventh at predicting survival overall.
- Editorial without indexed abstract.
- The N-stage change did not improve prognostic performance in validation.
Similar pages
not linked directly; found by shared links- Key paperSurgical Strategy for T2 Gallbladder Cancer According to Tumor Location
Shares Annals of surgical oncology, T2a versus T2b gallbladder cancer (peritoneal side versus hepatic side), Gallbladder cancer and the tag gallbladder-evidence.
- Key paperCarcinoma of the gallbladder: staging, treatment, and prognosis
Shares TNM staging, Gallbladder cancer roadmap: from a chance finding at gallstone surgery to a disease with its own trials, Gallbladder cancer and the tag gallbladder-evidence.
- IdeaA trial of sparing the liver resection in peritoneal-side (T2a) gallbladder cancer
Shares Tumor location is a strong predictor of tumor progression and survival in T2 gallbladder cancer: an international multicenter study, T2a versus T2b gallbladder cancer (peritoneal side versus hepatic side), Gallbladder cancer roadmap: from a chance finding at gallstone surgery to a disease with its own trials, Gallbladder cancer and the tag gallbladder-evidence.
- Key paperRe-resection in Incidental Gallbladder Cancer: Survival and the Incidence of Residual Disease
Shares Annals of surgical oncology, Gallbladder cancer roadmap: from a chance finding at gallstone surgery to a disease with its own trials, Gallbladder cancer and the tag gallbladder-evidence.
- Key paperPrognostic Significance of Tumor Location in T2 Gallbladder Cancer: A Systematic Review and Meta-Analysis
Shares T2a versus T2b gallbladder cancer (peritoneal side versus hepatic side), Gallbladder cancer roadmap: from a chance finding at gallstone surgery to a disease with its own trials, Gallbladder cancer and the tag gallbladder-evidence.
- Key paperOptimal surgical treatment in patients with T1b gallbladder cancer: An international multicenter study
Shares TNM staging, Gallbladder cancer roadmap: from a chance finding at gallstone surgery to a disease with its own trials, Gallbladder cancer and the tag gallbladder-evidence.
- Key paperTumor location and concurrent liver resection, impact survival in T2 gallbladder cancer: a meta-analysis of the literature
Shares T2a versus T2b gallbladder cancer (peritoneal side versus hepatic side), Gallbladder cancer and the tag gallbladder-evidence.
- IdeaTest whether T1b gallbladder cancer needs the second operation at all
Shares TNM staging, Gallbladder cancer roadmap: from a chance finding at gallstone surgery to a disease with its own trials, Gallbladder cancer and the tag gallbladder-evidence.