A randomized trial of minoxidil in chemotherapy-induced alopecia
Paper cited by one technology page, indexed on Europe PMC as PubMed record 8682968 and published in Journal of the American Academy of Dermatology; the citing page links this DOI, which is how the record was matched.
Overview
Background: Hair loss is a side effect of many chemotherapeutic agents, and patients have even refused possibly palliative or lifesaving drugs because they could not accept temporary or prolonged baldness. Topical minoxidil has been shown to be effective for androgenetic alopecia and alopecia areata.
Objective: Our purpose was to investigate the value and safety of minoxidil in chemotherapy-induced hair loss.
Methods: Twenty-two women who were facing adjuvant chemotherapy after breast surgery were registered in a protocol that used a 2% minoxidil topical solution or a placebo in a randomized double-blind trial.
Results: There was a statistically significant difference (favoring minoxidil) in the interval from maximal hair loss to first regrowth. Thus the period of baldness was shortened (mean, 50.2 days) in the minoxidil group.
Conclusion: Minoxidil decreased the duration of alopecia caused by chemotherapy. There were no significant side effects.
Indexed on Europe PMC as PubMed record 8682968 (DOI 10.1016/s0190-9622(96)90500-9). Matched by DOI alone: one technology page cites this DOI among its external links (the pages are listed under Related), and this page was written so that the citation resolves inside OnCo. No figure has been checked by an editor.
One technology page on OnCo cites this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing page listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
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