EANO guideline on the diagnosis and management of meningiomas (2021)
The European neuro-oncology guideline on meningioma sets out when to watch, when to operate, when to use radiosurgery or fractionated radiotherapy by grade and extent of resection, and the limited place of drug therapy.
Overview
Evidence-based guideline from the European Association of Neuro-Oncology covering imaging and molecular diagnosis of meningioma (including methylation and mutational classification), observation of incidental tumours, surgical goals and Simpson grading, radiosurgery and fractionated radiotherapy indications for grade 1 to 3 tumours, systemic therapy for refractory disease, and follow-up schedules.
Observation for small asymptomatic tumours, adjuvant radiotherapy for incompletely resected grade 2 and all grade 3 tumours, and the referral of refractory cases to trials on this site's meningioma page follow this guideline.
- Randomised evidence for adjuvant radiotherapy in grade 2 meningioma is still awaited from ongoing trials.