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Fifteen Spanish cancer registries looked at cancers in adults aged 20 to 49 from 1993 to 2018: smoking-related cancers fell sharply, while some obesity-related cancers rose in people under 40.
Published as "Is cancer increasing in young adults in Spain? Incidence trends from the Spanish Network of Cancer Registries (REDECAN)". A population-based study within REDECAN using data from 15 cancer registries included every new cancer diagnosed in people aged 20 to 49 between 1993 and 2018, 153,599 cases, 58% of them in women. Truncated age-standardised incidence rates were calculated with the European standard population and trends assessed with Joinpoint regression to estimate the annual percent change. A corrigendum was published in September 2026 (DOI 10.1016/j.ejca.2026.116950).
Spain's registries see the same early-onset signal reported elsewhere, but not across the board: in young adults smoking-related cancers have fallen while some obesity-associated cancers have risen, which points prevention at weight and diet as well as tobacco.
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