OnCo

Sign in to keep your watchlist

Your watched pages live in this browser. Sign in with an email link and OnCo keeps the same list on every device you use. Only your email address and your watchlist are stored.

Living with cancer· Appointment prep

Appointment sheet: BRAF V600E-mutant non-small-cell lung cancer

One page to bring and write on: your details, the questions for BRAF V600E-mutant non-small-cell lung cancer plus your own, the words you may hear, what to bring, the treatments the standard of care names, and room for the answers and agreed next steps. What you type stays in this browser. Print it or save it as a PDF. New to all this? Start with the first 60 days. Orientation, not medical advice.

Tick the questions to print

All of this cancer's questions start ticked. Untick what does not apply; ticks are kept in this browser. .

Your own questions

Shared with the prep pack, so questions you add there appear here too.

Print or save as PDF

Use (or Ctrl+P, Cmd+P on a Mac). To keep a copy, choose Save as PDF as the destination in the print dialog. Only the sheet prints; the controls stay on screen. Your typed notes print where you typed them; empty fields print as ruled lines to write on.

Appointment sheet

BRAF V600E-mutant non-small-cell lung cancer

Prepared with OnCo (onco.cc/prep/braf-v600e-nsclc/). Orientation, not medical advice; your team knows your case.

My details

Name
Date of appointment
Hospital and clinician
Who is coming with me

What I know, what is unclear, changes to discuss

Saved in this browser
What I know so far
What is unclear to me
Changes since last time

My questions

16 on the sheet
Newly diagnosed
  1. 1.What is my exact diagnosis, stage, and grade, and which tests established them?
  2. 2.Which biomarkers have been tested on my tumour (for example BRAF V600E by sequencing, BRAF mutation class, PD-L1 tumour proportion score, Left ventricular function, eye examination and temperature on BRAF plus MEK inhibitors), and what were the results?
  3. 3.Which subtype is my cancer, and does that change the recommended treatment?
  4. 4.Is germline (inherited) genetic testing recommended for me or my family?
Advanced BRAF V600E, first line
  1. 5.For my situation (advanced braf v600e, first line), which of the standard options do you recommend and why?
  2. 6.Am I a candidate for Dabrafenib + trametinib, Dabrafenib, Trametinib or related drugs, and what side effects should I expect?
  3. 7.How do the results of PHAROS apply to someone like me?
Advanced BRAF V600E, after targeted therapy
  1. 8.For my situation (advanced braf v600e, after targeted therapy), which of the standard options do you recommend and why?
  2. 9.Am I a candidate for Pembrolizumab, Carboplatin, Pemetrexed or related drugs, and what side effects should I expect?
Non-V600 BRAF mutations
  1. 10.For my situation (non-v600 braf mutations), which of the standard options do you recommend and why?
  2. 11.Am I a candidate for Pembrolizumab, Carboplatin, Pemetrexed or related drugs, and what side effects should I expect?
Any stage
  1. 12.Are there clinical trials I could join, for example of PHAROS, Encorafenib, Binimetinib?
  2. 13.Would a second opinion at a high-volume centre change anything, and can you help arrange it?
  3. 14.What supportive care (symptom control, nutrition, exercise, mental health, financial help) is available from the start?
  4. 15.I read that “No randomised trial compares BRAF plus MEK inhibitors with chemoimmunotherapy first line or settles the sequence”. How does that affect my plan?
  5. 16.I read that “Non-V600 BRAF mutations, half of cases, have no approved targeted therapy”. How does that affect my plan?

The words I may hear

Tests and results to bring

Biomarker results to ask for: BRAF V600E by sequencing (immunohistochemistry as a screen), BRAF mutation class (V600 versus non-V600), PD-L1 tumour proportion score (immunotherapy is active in BRAF-mutant disease), Left ventricular function, eye examination and temperature on BRAF plus MEK inhibitors.

Scans and tests linked to this cancer: Comprehensive genomic profiling.

Bring copies of scan reports, pathology and blood results, and a list of every medicine and supplement.

The treatments I may be offered

From the standard of care recorded for this cancer; which apply depends on your stage and biomarkers. Ask which the team recommends and why.

Answers and next steps

Saved in this browser
What I was told
Agreed next steps, dates and who to call