Serrated adenocarcinoma of the colon and rectum
Prepared with OnCo (onco.cc/prep/colorectal-serrated-adenocarcinoma/). Orientation, not medical advice; your team knows your case.
My details
What I know, what is unclear, changes to discuss
Saved in this browserMy questions
8 on the sheet- 1.What is my exact diagnosis, stage, and grade, and which tests established them?
- 2.Which biomarkers have been tested on my tumour (for example BRAF V600E and KRAS mutation, Mismatch repair status and MLH1 methylation, MGMT loss, CpG island methylator phenotype), and what were the results?
- 3.Which subtype is my cancer, and does that change the recommended treatment?
- 4.Is germline (inherited) genetic testing recommended for me or my family?
- 5.For my situation (all stages), which of the standard options do you recommend and why?
- 6.Am I a candidate for Encorafenib, Cetuximab, and what side effects should I expect?
- 7.Would a second opinion at a high-volume centre change anything, and can you help arrange it?
- 8.What supportive care (symptom control, nutrition, exercise, mental health, financial help) is available from the start?
Tests and results to bring
Biomarker results to ask for: BRAF V600E and KRAS mutation, Mismatch repair status and MLH1 methylation, MGMT loss, CpG island methylator phenotype (research).
Bring copies of scan reports, pathology and blood results, and a list of every medicine and supplement.
The treatments I may be offered
- All stages: Treated as the colorectal page by stage and molecular status: encorafenib with cetuximab for BRAF V600E metastatic disease, checkpoint inhibitors for MSI-high disease. (Colorectal cancer, BRAF V600E-mutant colorectal cancer, Encorafenib, Cetuximab)
From the standard of care recorded for this cancer; which apply depends on your stage and biomarkers. Ask which the team recommends and why.