Appointment sheet
Lobular carcinoma in situ (LCIS)
Prepared with OnCo (onco.cc/prep/lobular-carcinoma-in-situ/). Orientation, not medical advice; your team knows your case.
My details
Name
Date of appointment
Hospital and clinician
Who is coming with me
What I know, what is unclear, changes to discuss
Saved in this browserWhat I know so far
What is unclear to me
Changes since last time
My questions
10 on the sheetNewly diagnosed
- 1.What is my exact diagnosis, stage, and grade, and which tests established them?
- 2.Which biomarkers have been tested on my tumour (for example E-cadherin loss, Oestrogen receptor, Pleomorphic or florid morphology, Extent on MRI when considering excision), and what were the results?
- 3.Which subtype is my cancer, and does that change the recommended treatment?
- 4.Is germline (inherited) genetic testing recommended for me or my family?
Classic LCIS on biopsy
- 5.For my situation (classic lcis on biopsy), which of the standard options do you recommend and why?
- 6.Am I a candidate for Tamoxifen, and what side effects should I expect?
- 7.How do the results of TAM-01 apply to someone like me?
Pleomorphic or florid LCIS
- 8.For my situation (pleomorphic or florid lcis), which of the standard options do you recommend and why?
Any stage
- 9.Would a second opinion at a high-volume centre change anything, and can you help arrange it?
- 10.What supportive care (symptom control, nutrition, exercise, mental health, financial help) is available from the start?
The words I may hear
- Aromatase inhibitor: Pills that stop the body making oestrogen (after the menopause, when it comes from fat and muscle rather than the ovaries), starving hormone receptor-positive breast cancer.
- Carcinoma in situ (CIS): Cancer cells that fill the lining layer where they started but have not broken through the basement membrane into the tissue beneath.
- Mastectomy: Removing the whole breast, either for cancer or preventively in BRCA1/2 carriers, where bilateral risk-reducing mastectomy cuts breast cancer risk by 90% or more.
Tests and results to bring
Biomarker results to ask for: E-cadherin loss, Oestrogen receptor (positive in classic LCIS), Pleomorphic or florid morphology (upgrade risk), Extent on MRI when considering excision.
Bring copies of scan reports, pathology and blood results, and a list of every medicine and supplement.
The treatments I may be offered
- Classic LCIS on biopsy: Surveillance and chemoprevention (tamoxifen or an aromatase inhibitor); TAM-01 tested low-dose tamoxifen in intraepithelial neoplasia. (Tamoxifen, TAM-01, Aromatase inhibitor)
- Pleomorphic or florid LCIS: Excision to clear margins because of the upgrade rate to invasive cancer or ductal carcinoma in situ. (Ductal carcinoma in situ (DCIS), Mastectomy)
From the standard of care recorded for this cancer; which apply depends on your stage and biomarkers. Ask which the team recommends and why.
Answers and next steps
Saved in this browserWhat I was told
Agreed next steps, dates and who to call