OnCo

VeIP

Checked 2026-09-09

Second-line (salvage) chemotherapy for relapsed germ cell tumours after BEP

Also called VeIP (vinblastine, ifosfamide, cisplatin).

One cycle

every 21 days × 4 · about 12 weeks in total
178141521Vinblastine: 0.11 mg/kg, IntravenousVinblastineIfosfamide: 1,200 mg/m² with mesna, IntravenousIfosfamideCisplatin: 20 mg/m², IntravenousCisplatin
21-day cycle × 4 (about 12 weeks)Intravenous

Components

DrugDoseRouteDays
Vinblastine
Vinca alkaloid (microtubule inhibitor)
0.11 mg/kgIVD1, 2
Ifosfamide
Cytotoxic chemotherapy (alkylating agent)
1,200 mg/m² with mesnaIVD1-5
Cisplatin
Cytotoxic chemotherapy (platinum)
20 mg/m²IVD1-5
Cycles
4
21-day cycle
Emetogenicity
High (>90%)
G-CSF
Recommended

Notes

  • Alternatives are TIP (paclitaxel, ifosfamide, cisplatin) and high-dose chemotherapy with stem cell rescue.

Used in

Source

Loehrer, JCO 1998: vinblastine plus ifosfamide plus cisplatin as salvage therapy

Reference doses for a typical adult from the cited protocol or label. Doses are adjusted for renal and hepatic function, age, performance status and prior toxicity, and institutional protocols vary. Verify against the current label and your local protocol before treating. Not medical advice.

Other regimens for these cancers