OnCo

Neuroendocrine carcinoma of the gallbladder: lines of therapy

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2 standard-of-care settings across 2 lines and 2 biomarker subgroups. Rows come from the cancer page's standard of care; the grid places each on its line and subgroup.

LineAll comersHR-positive
Early / localised1·
Advanced, first line·1

Early / localised

SubgroupSettingApproachProducts and trialsEvidence
All comersLocalised diseaseResection as for gallbladder cancer where feasible; surgery and adjuvant chemotherapy were each associated with better survival in population data.-

Advanced, first line

SubgroupSettingApproachProducts and trialsEvidence
HR-positiveAdvanced diseasePlatinum and etoposide chemotherapy as for other extrapulmonary neuroendocrine carcinomas, rather than the gemcitabine and cisplatin used for adenocarcinoma.81

Lines and subgroups are parsed from the setting text of each standard-of-care row and can misclassify an unusual phrasing; the row’s own setting is always shown. Guideline chips reflect the NCCN category and ESMO-MCBS grade recorded on the cancer page, checked on its stated date. Not medical advice.