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Cancers & treatments·Sequencing

Localised prostate cancer, intermediate risk: lines of therapy

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3 standard-of-care settings across 2 lines and 2 biomarker subgroups. Rows come from the cancer page's standard of care; the grid places each on its line and subgroup.

LineAll comersRisk group
Early / localised·2
Other settings1·

Early / localised

SubgroupSettingApproachProducts and trialsEvidence
Risk groupFavourable intermediate riskRadical prostatectomy, external beam radiotherapy (moderate or ultra-hypofractionated) or brachytherapy alone; active surveillance for selected men with low volume Grade Group 2 disease.
Robotic & minimally invasive surgeryHypofractionated radiotherapySBRT / SABR (stereotactic radiotherapy)BrachytherapyActive surveillanceCHHiPPACE-B
71
Risk groupUnfavourable intermediate riskRadical prostatectomy with pelvic lymph node dissection, or external beam radiotherapy with four to six months of androgen deprivation, or external beam plus brachytherapy boost.
Robotic & minimally invasive surgeryAndrogen deprivation & AR pathway inhibitorsLeuprolide (leuprorelin) and GnRH agonistsBrachytherapyIMRT / IGRT (modern external beam)HYPO-RT-PC
95

Other settings

SubgroupSettingApproachProducts and trialsEvidence
All comersDeciding on hormone therapyArteraAI Prostate predicts benefit from short-course androgen deprivation with radiotherapy; Decipher stratifies risk.
ArteraAI ProstateDecipher ProstateDigital pathology & AI
58

Lines and subgroups are parsed from the setting text of each standard-of-care row and can misclassify an unusual phrasing; the row’s own setting is always shown. Guideline chips reflect the NCCN category and ESMO-MCBS grade recorded on the cancer page, checked on its stated date. Not medical advice.