OnCo
drugsProductApproved2025

ArteraAI Prostate

The first AI tool cleared by the FDA to predict both prognosis and treatment benefit from a routine biopsy slide, in prostate cancer.

De novo authorisation August 2025. Multimodal AI on H&E biopsy images plus clinical variables predicts distant metastasis and benefit from short-term androgen deprivation with radiotherapy (validated on NRG/RTOG trial cohorts). NCCN-listed.

Schematic of the modality · AI digital pathology prognostic/predictive test · not a molecule; see the Digital pathology & AI page
Mechanism, step by step
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1.Biopsy slides are scanned to digital images

Modality
AI digital pathology prognostic/predictive test
Mechanism
Deep-learning image encoder plus clinical data fusion.
Medicare
Part B (clinician-administered)

Digital pathology prognostic test covered by Medicare for localised prostate cancer through the MolDX programme (Palmetto GBA local coverage) since 2023; billed as a laboratory test under Part B with no coinsurance.

Commercial insurance
variable

Commercial coverage is limited and case by case; the lab often bills the patient after a coverage denial or offers a financial assistance programme.

Sources: Medicare.gov: Chemotherapy · Medicare.gov: Prescription drugs (outpatient, Part B) · Medicare.gov: Clinical laboratory tests · CMS Medicare Coverage Database (NCDs and LCDs). Not medical or financial advice; verify with your plan.

Not appraisedSearch NICE
Notes
Not available on the NHS; NICE early value assessment route applies to digital prognostic tools.
NHS England
Not routinely funded

Sources: NICE search: ArteraAI Prostate. Funding decisions are indication-specific and change monthly; verify with NICE and your treating team.

Regulatory

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  1. 14 Aug 2025ApprovalUS

    De novo authorisation: first AI pathology test cleared for prognostic and predictive use in localised prostate cancer source

Approvals

RegionYearIndication
US2025Localised prostate cancer risk stratification and ADT benefit prediction

Cost & access

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Cost & access
CountryReimbursement
United StatesMedicare coverage via MolDX; NCCN-listed

List prices are manufacturer or Medicare figures where publicly disclosed; net prices after rebates are usually lower. Reimbursement changes; check the payer.

Trials

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Recruiting now (live from ClinicalTrials.gov)

Recruiting trials near you · live from ClinicalTrials.gov
ArteraAI Prostate
intervention: ArteraAI Prostate
Open on ClinicalTrials.gov →

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Latest papers

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Literature trend1 papers in the last 12 months-80% vs prior 12How this is computed
Latest papers · live from Europe PMC
Open in Europe PMC

Query for this drug: (TITLE:"ArteraAI Prostate" OR ABSTRACT:"ArteraAI Prostate") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about ArteraAI Prostate, not a curated reading list.

Connected

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