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No description yet: the sentence for this tag has not been written. 2 records carry it: 1 person, 1 key paper.
| Cancers | Other tags | ||||
|---|---|---|---|---|---|
A preinvasive regulatory T cell axis for lung cancer interception Gamble S, Whiteman ZE, Peinador-Marín C, et al. · Nature 2026 Before lung cancer becomes invasive, a family of immune-dampening cells (effector regulatory T cells) builds up in the precancerous airway lining and in the blood, and rising levels marked people whose early cancers grew fast. In mice, blocking the PI3K-delta signal these cells depend on reduced lung tumours. | Lung cancer, Non-small-cell lung cancer | landmark-watch, interception | |||
Shimon Sakaguchi Distinguished Professor, Immunology Frontier Research Center, Osaka University · Osaka University Graduate School of Medicine / Osaka University Hospital Discovered regulatory T cells, the immune cells that suppress anti-tumour responses and are now a target for cancer therapy. | none | none | immunology, discovery, japan |