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No description yet: the sentence for this tag has not been written. 7 records carry it: 7 people.
| Cancers | Other tags | ||||
|---|---|---|---|---|---|
Aaron Ciechanover Distinguished Research Professor, Rappaport-Technion Integrated Cancer Center and Rappaport Faculty of Medicine, Technion · Technion, Israel Institute of Technology Shared the 2004 Nobel Prize in Chemistry for discovering how cells label proteins for destruction. That labelling system is what proteasome inhibitors block and what every protein degrader hijacks. | Multiple myeloma | none | nobel-laureate, cancer-biology | ||
Avram Hershko Distinguished Professor, Department of Biochemistry, Rappaport Faculty of Medicine, Technion · Technion, Israel Institute of Technology Shared the 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation, and still works on how the machinery that destroys proteins controls cell division. | none | none | nobel-laureate, cancer-biology | ||
Michal Besser Head of the Ella Lemelbaum Institute cell therapy laboratory, Sheba Medical Center; Gray Faculty of Medical and Health Sciences, Tel Aviv University · Sheba Medical Center Runs the laboratory that actually grows the cells. Her papers are the reason anyone outside the United States believed a hospital could manufacture tumour-infiltrating lymphocytes reliably. | Melanoma | none | cell-therapy | ||
Moshe Oren Professor, Department of Molecular Cell Biology, Weizmann Institute of Science · Weizmann Institute of Science Cloned p53 and then spent a career on what it does. The field's first reading of his own 1984 result, that p53 was an oncogene, turned out to be wrong, and the correction is the better story. | none | none | cancer-biology | ||
Yardena Samuels Professor, Department of Molecular Cell Biology, Weizmann Institute of Science · Weizmann Institute of Science She found that PIK3CA is one of the most frequently mutated genes in human cancer, then spent the next twenty years working out which of a melanoma's mutations the immune system can actually see. | Melanoma | none | genomics, immunology | ||
Yechezkel Barenholz Professor, Laboratory of Membrane and Liposome Research, Hebrew University-Hadassah Medical School · Hebrew University of Jerusalem Invented the chemistry that made Doxil work, the first nanomedicine any regulator approved, which is still a standard treatment for relapsed ovarian cancer three decades later. | Ovarian cancer, Kaposi sarcoma | none | drug-delivery | ||
Yosef Yarden Professor, Department of Immunology and Regenerative Biology, Weizmann Institute of Science · Weizmann Institute of Science One of the people who worked out what the HER family of receptors does and how antibodies against them behave, including why combining two antibodies against the same receptor works better than either alone. | HER2-positive breast cancer, Non-small-cell lung cancer | none | cancer-biology |