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Histology automation and IHC autostainers

Histology automation is the robots that process tissue into slides and stain them for biomarkers such as HER2 and PD-L1, the same way every time.

Tissue processors, embedding stations, and microtomes (Sakura Tissue-Tek, Leica, Epredia) feed IHC/ISH autostainers (Roche VENTANA BenchMark ULTRA, Leica BOND, Agilent Dako Omnis, Sakura Tissue-Tek Genie) that run FDA-approved companion assays under locked protocols; staining platform, clone, and scoring guide are label-specific. Lab automation and tracking (barcoded cassettes and slides) reduce misidentification errors.

Generic schematic · not to scale · placeholder for the diagnostics front
Molecular read-out

How it works

Automated reagent dispensing, incubation, and detection chemistry on slides with barcode-driven protocols and on-board quality controls.

Strengths
  • Reproducibility across labs
  • Regulatory-approved closed assays
Limitations
  • Vendor lock-in to reagent ecosystems
  • Assays not interchangeable across platforms
  • Capital cost for small labs

Latest papers

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