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A phase 1/2 trial of pembrolizumab, trifluridine/tipiracil and fluorouracil (5-FU) in pancreatic cancer, run by Kyushu University, now recruiting.
GAIA-102 Intraperitoneal Administration in Patients With Advanced Gastrointestinal Cancer of Microsatellite Stable With Malignant Ascites is a phase 1/2, randomised interventional study registered as NCT05438459 by Kyushu University, with a registry enrolment figure of 176 participants, started 2022-06-08 and due to reach its primary completion in 2032-03-31. Interventions recorded: GAIA-102; GAIA-102; Pembrolizumab; Pembrolizumab; Trifluridine/tipiracil hydrochloride (FTD/TPI); Irinotecan hydrochloride hydrate; Calcium levofolinate hydrate; Fluorouracil. Conditions listed: Gastric Cancer; Pancreatic Cancer. Primary outcome: Number of participants of Dose Limiting Toxicity (DLT) with GAIA-102 (Phase I); Frequency and severity of adverse events(Phase I); Overall survival in patients with gastric cancer (Phase II). Pancreatic eligibility wording from the registry: "* Unresectable or advanced recurrent gastric cancer with evident peritoneal dissemination on imaging, or with malignant ascites, as well as unresectable or advanced recurrent pancreatic cancer". Sites: Japan. No results are recorded here; the registry entry is the source.
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Shares Fluorouracil (5-FU), Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Cytotoxic chemotherapy and the tag pancreatic-deep-dive.
Shares Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma, Pembrolizumab, Immune checkpoint inhibitors and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma, Cytotoxic chemotherapy and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma, Cytotoxic chemotherapy and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma, Immune checkpoint inhibitors and the tag pancreatic-deep-dive.