Assess the Efficacy of Radiotherapy and Sequential Chemotherapy and AK104 Before TME Surgery for Local CRC（AK104-IIT-13）

Assess the Efficacy of Radiotherapy and Sequential Chemotherapy and AK104 Before TME Surgery for Local CRC（AK104-IIT-13） is a phase 2, interventional study registered as NCT05794750 by JIN JING, with a registry enrolment figure of 50 participants, started 2023-04-24 and due to reach its primary completion in 2027-04-24. Interventions recorded: AK104 injection; TME surgery; Capecitabine; Oxaliplatin. Conditions listed: Locally Advanced Rectal Cancer. Primary outcome: Pathologic complete response rate (pCR). Colorectal eligibility wording from the registry: "Fiber colonoscopy or diagnosis examination, the lower boundary of the lesion is 15m ≤ from the margin;". No results are recorded here; the registry entry is the source.