Loading
A phase 2 trial of trifluridine/tipiracil, fOLFOX (5-FU, leucovorin, oxaliplatin), panitumumab, bevacizumab (glioblastoma use) and other drugs in colorectal cancer, run by UNICANCER, now recruiting.
Safety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Metastatic Colorectal or Gastroesophageal Cancer is a phase 2, interventional study registered as NCT06245356 by UNICANCER, with a registry enrolment figure of 73 participants, started 2025-03-21 and due to reach its primary completion in 2026-10-22. Interventions recorded: Lonsurf; Oxaliplatin; Panitumumab; Bevacizumab; Trastuzumab; Nivolumab. Conditions listed: Metastatic Colorectal Cancer; Metastatic Gastroesophageal Adenocarcinoma; DPD Deficiency. Primary outcome: Treatment specific safety. Colorectal eligibility wording from the registry: "Histological or cytological documentation of adenocarcinoma of the colon or rectum or gastroesophageal cancer (lower oesophagus, gastroesophageal junction and gastric)". Sites: France. No results are recorded here; the registry entry is the source.
Shares Trifluridine/tipiracil, Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Platinum agents and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Platinum agents, Monoclonal antibodies and the tag colorectal-deep-dive.
Shares Servier, Trifluridine/tipiracil, Bevacizumab (glioblastoma use), Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Platinum agents, Monoclonal antibodies and the tag colorectal-deep-dive.