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A phase 1/2 trial of sintilimab and fOLFIRINOX / mFOLFIRINOX in pancreatic cancer, run by First Affiliated Hospital of Zhejiang University, now recruiting.
Bortezomib Combined with PD-1 MAb and MFOLFIRINOX for Metastatic Pancreatic Cancer is a phase 1/2, interventional study registered as NCT06572813 by First Affiliated Hospital of Zhejiang University, with a registry enrolment figure of 63 participants, started 2024-11-15 and due to reach its primary completion in 2026-09-01. Interventions recorded: Bortezomib Injection; Sintilimab; mFOLFIRINOX. Conditions listed: Pancreas Cancer. Primary outcome: Phase 1: Number of participants with treatment-related adverse events as assessed by CTCAE v5.0; Phase 2: Objective reponse rate (ORR). Pancreatic eligibility wording from the registry: "* Pathologically (histologically or cytologically) confirmed pancreatic ductal adenocarcinoma (PDAC)". Sites: China. No results are recorded here; the registry entry is the source.
Shares FOLFIRINOX / mFOLFIRINOX, Topoisomerase-I inhibitors (and ADC payloads), Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares FOLFIRINOX / mFOLFIRINOX, Topoisomerase-I inhibitors (and ADC payloads), Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares FOLFIRINOX / mFOLFIRINOX, Topoisomerase-I inhibitors (and ADC payloads), Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares FOLFIRINOX / mFOLFIRINOX, Topoisomerase-I inhibitors (and ADC payloads), Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares FOLFIRINOX / mFOLFIRINOX, Topoisomerase-I inhibitors (and ADC payloads), Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares FOLFIRINOX / mFOLFIRINOX, Topoisomerase-I inhibitors (and ADC payloads), Platinum agents, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares Sintilimab, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma, Cytotoxic chemotherapy and the tag pancreatic-deep-dive.
Shares Sintilimab, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma, Immune checkpoint inhibitors and the tag pancreatic-deep-dive.