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A phase 2 trial of regorafenib, fluorouracil (5-FU), leucovorin (folinic acid), bevacizumab (glioblastoma use) and other drugs in colorectal cancer, run by The Methodist Hospital Research Institute, now recruiting.
5-Fluorouracil/Leucovorin (5FU/LV) in Combination With Regorafenib in Patients With Metastatic Colorectal Cancer is a phase 2, randomised interventional study registered as NCT06887218 by The Methodist Hospital Research Institute, with a registry enrolment figure of 57 participants, started 2025-05-08 and due to reach its primary completion in 2028-12. Interventions recorded: Regorafenib (BAY 73-4506); 5FU/LV; Bevacizumab; Trifluridine-tipiracil. Conditions listed: Metastatic Colorectal Cancer (CRC). Primary outcome: Efficacy of 5FU/LV in combination with regorafenib in metastatic colorectal cancer. Colorectal eligibility wording from the registry: "Active or recent (within 3 years) non-colorectal cancer malignancies, except for low-risk, cured cancers (e". Sites: United States. No results are recorded here; the registry entry is the source.
Shares Regorafenib, Bevacizumab (glioblastoma use), Anti-angiogenic therapy, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Leucovorin (folinic acid), Fluorouracil (5-FU), Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Leucovorin (folinic acid), Fluorouracil (5-FU), Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Regorafenib, Bevacizumab (glioblastoma use), Anti-angiogenic therapy, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Trifluridine/tipiracil, Bevacizumab (glioblastoma use), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Trifluridine/tipiracil, Bevacizumab (glioblastoma use), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Trifluridine/tipiracil, Bevacizumab (glioblastoma use), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Leucovorin (folinic acid), Anti-angiogenic therapy, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.