A phase 1/2 trial of serplulimab in pancreatic cancer, run by West China Hospital, not yet recruiting.
JDB153 Combined With Serplulimab for Pancreatic Cancer After Standard Treatment Failure is a phase 1/2, interventional study registered as NCT07175389 by West China Hospital, with a registry enrolment figure of 10 participants, started 2026-09-01 and due to reach its primary completion in 2028-09-01. Interventions recorded: JDB153; Serplulimab. Conditions listed: Refractory Pancreatic Ductal Adenocarcinoma; Refractory Pancreatic Adenocarcinoma. Primary outcome: Incidence of Treatment-Related Adverse Events; Objective Response Rate (ORR). Pancreatic eligibility wording from the registry: "* 1\) Histologically or cytologically confirmed diagnosis of locally advanced, unresectable, or metastatic pancreatic cancer; 2) Age 18-75 years, inclusive; no sex restrictions; 3) Life expectancy ≥12 weeks; 4) Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1; 5) Documented dis". Sites: China. No results are recorded here; the registry entry is the source.
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Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma, Immune checkpoint inhibitors and the tag pancreatic-deep-dive.
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