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A phase 2 trial of ivonescimab, carboplatin, pemetrexed, paclitaxel / nab-paclitaxel and other drugs in lung cancer, run by European Organisation for Research and Treatment of Cancer - EORTC, not yet recruiting.
Phase II Study of Upfront SRT Plus Ivonescimab/Chemotherapy vs Ivonescimab/Chemotherapy in NSCLC Brain Mets is a phase 2, randomised interventional study registered as NCT07234877 by European Organisation for Research and Treatment of Cancer - EORTC, with a registry enrolment figure of 158 participants, started 2026-11 and due to reach its primary completion in 2032-01. Interventions recorded: Ivonescimab; Carboplatin; Pemetrexed; Paclitaxel; Paclitaxel-albumin; Stereotactic Radiosurgery (SRS) or Fractionated Stereotactic Radiotherapy (FSRT). Conditions listed: Non Small Cell Lung Cancer. Primary outcome: Intracranial progression-free survival based on local assessment using RANO-BM criteria. Lung eligibility wording from the registry: "* Patients with pathology proven metastatic NSCLC without an actionable genomic alteration for which there is first line targeted treatment approved by EMA and recommended by the ESMO guidelines". Sites: Austria, France, Germany, Greece, Italy, Netherlands, Slovenia, Spain. No results are recorded here; the registry entry is the source.
Shares Summit Therapeutics, Ivonescimab, Bispecific antibodies, Pemetrexed and the tag lung-deep-dive.
Shares Summit Therapeutics, Ivonescimab, Bispecific antibodies, SBRT / SABR (stereotactic radiotherapy) and the tag lung-deep-dive.
Shares Nab-paclitaxel, Pemetrexed, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel and the tag lung-deep-dive.
Shares Nab-paclitaxel, Pemetrexed, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel and the tag lung-deep-dive.
Shares Bispecific antibodies, Pemetrexed, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel and the tag lung-deep-dive.
Shares Nab-paclitaxel, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel, Platinum agents and the tag lung-deep-dive.
Shares Ivonescimab, Bispecific antibodies, Anti-angiogenic therapy, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin and the tag lung-deep-dive.