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A phase 2 trial of trastuzumab deruxtecan, capecitabine and bevacizumab (glioblastoma use) in colorectal cancer, run by Gruppo Oncologico del Nord-Ovest, now recruiting.
Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer. is a phase 2, interventional study registered as NCT07407465 by Gruppo Oncologico del Nord-Ovest, with a registry enrolment figure of 42 participants, started 2025-10-20 and due to reach its primary completion in 2027-10-20. Interventions recorded: Trastuzumab-Deruxtecan (T-DXd); Capecitabine; Bevacizumab. Conditions listed: Colorectal Cancer; Colorectal Adenocarcinoma; Rectal Adenocarcinoma; Rectal Cancer, Adenocarcinoma; Rectal Cancer, Metastatic; Colon Cancer Metastatic; Colon Cancer Adenocarcinoma. Primary outcome: Overall Response Rate. Colorectal eligibility wording from the registry: "* Have histologically documented adenocarcinoma of the colon or rectum, which is initially metastatic or unresectable locally advanced". Sites: France, Germany, Italy, Spain. No results are recorded here; the registry entry is the source.
Shares Bevacizumab (glioblastoma use), Capecitabine, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Capecitabine, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Capecitabine, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Capecitabine, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Capecitabine, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Capecitabine, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.