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A phase 2 trial of serplulimab in triple-negative breast cancer, run by Shanghai Henlius Biotech, not yet recruiting.
Phase II Study of HLX43 Monotherapy or Combined With Immune Checkpoint Inhibitors in Patients With Locally Advanced, Recurrent, or Metastatic Triple-negative Breast Cancer. is a phase 2, randomised interventional study registered as NCT07487519 by Shanghai Henlius Biotech, with a registry enrolment figure of 180 participants, started 2026-04-25 and due to reach its primary completion in 2027-05-15. Interventions recorded: HLX43 DOSE 1 IN ≥2L TNBC; HLX43 DOSE 2 IN ≥2L TNBC; HLX43 DOSE 1 + HLX10; HLX43 DOSE1 IN 1L TNBC; HLX43 DOSE 2 IN 1L TNBC; HLX43 DOSE2 + HLX10. Conditions listed: Breast Cancer (Triple Negative Breast Cancer (TNBC)). Triple-negative eligibility wording from the registry: "Histopathologically confirmed TNBC: ER \< 1%, PR \< 1%, HER2 IHC 0/1+/2+ with no FISH amplification". Sites: China. No results are recorded here; the registry entry is the source.
Shares Metastatic triple-negative breast cancer, Triple-negative breast cancer trials open today (registry snapshot and UK sites), Immune checkpoint inhibitors and the tag tnbc-deep-dive.
Shares Metastatic triple-negative breast cancer, Triple-negative breast cancer trials open today (registry snapshot and UK sites), Immune checkpoint inhibitors and the tag tnbc-deep-dive.
Shares Metastatic triple-negative breast cancer, Triple-negative breast cancer trials open today (registry snapshot and UK sites), Immune checkpoint inhibitors and the tag tnbc-deep-dive.
Shares Metastatic triple-negative breast cancer, Triple-negative breast cancer trials open today (registry snapshot and UK sites), Immune checkpoint inhibitors and the tag tnbc-deep-dive.
Shares Metastatic triple-negative breast cancer, Triple-negative breast cancer trials open today (registry snapshot and UK sites) and the tag tnbc-deep-dive.
Shares Metastatic triple-negative breast cancer, Triple-negative breast cancer trials open today (registry snapshot and UK sites) and the tag tnbc-deep-dive.
Shares Metastatic triple-negative breast cancer, Triple-negative breast cancer trials open today (registry snapshot and UK sites) and the tag tnbc-deep-dive.
Shares Metastatic triple-negative breast cancer, Triple-negative breast cancer trials open today (registry snapshot and UK sites) and the tag tnbc-deep-dive.