Serine/Glycine-Restricted Diet With Chemoradiotherapy for Rectal Cancer

Serine/Glycine-Restricted Diet With Chemoradiotherapy for Rectal Cancer is a phase 1/2, randomised interventional study registered as NCT07811076 by Xuelei Ma MD, with a registry enrolment figure of 140 participants, started 2026-08-31 and due to reach its primary completion in 2027-01-31. Interventions recorded: Serine/Glycine-Restricted Diet; CAPOX Chemotherapy; PD-1 Inhibitor; Short-Course Radiotherapy. Conditions listed: Locally Advanced Rectal Cancer (LARC). Primary outcome: Complete Response Rate (pCR + cCR). Colorectal eligibility wording from the registry: "* Histologically confirmed locally advanced rectal cancer staged as cT3, cT4, or node-positive by pelvic MRI". Sites: China. No results are recorded here; the registry entry is the source.