A phase 2 trial of serplulimab, cAPOX (capecitabine, oxaliplatin) and bevacizumab (glioblastoma use) in colorectal cancer, run by Xijing Hospital, not yet recruiting.
Serplulimab Combined With CAPOX and Bevacizumab as Neoadjuvant Therapy for Locally Advanced Colorectal Cancer is a phase 2, interventional study registered as NCT07819604 by Xijing Hospital, with a registry enrolment figure of 85 participants, started 2026-09-01 and due to reach its primary completion in 2027-09-01. Interventions recorded: Serplulimab; CAPOX; Bevacizumab. Conditions listed: Locally Advanced Colorectal Cancer. Primary outcome: Pathological Complete Response (pCR) Rate. Colorectal eligibility wording from the registry: "* Histologically or pathologically confirmed locally advanced rectal adenocarcinoma, cT3/cT4N+M0 stage per AJCC/UICC 8th edition, with distance from anal verge ≤10 cm". No results are recorded here; the registry entry is the source.
Shares Serplulimab, Bevacizumab (glioblastoma use), Platinum agents, Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Serplulimab, Platinum agents, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Serplulimab, Platinum agents, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.