What changed: BRAF V600E-mutant colorectal cancer

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Every dated change on the records linked to BRAF V600E-mutant colorectal cancer, newest first: approvals and regulatory steps on its medicines, trials that reported, guideline versions, milestones, and when this page itself was checked. Dates come from the records; none is inferred. Orientation, not medical advice.

Trial result4Milestone7This record1

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September 2026 · 1

2026-09-17This recordBRAF V600E-mutant colorectal cancer
Facts on this page last checked
When this page itself was last checked or edited.

2026 · 1

2026MilestoneEncorafenib
Full approval of the first-line triplet
A milestone in how this cancer is treated.

2025 · 2

2024 · 2

2020 · 2

2019 · 2

2011 · 1

2011MilestoneBRAF
Vemurafenib alone fails in BRAF-mutant colorectal cancer; EGFR feedback identified the next year
A milestone in how this cancer is treated.

2002 · 1

2002MilestoneBRAF
BRAF mutations discovered in human cancer (Davies, Nature)
A milestone in how this cancer is treated.