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Everything in development, the open problems and what is being done about them, the roadmaps, and what changed on this record.
What is in development for Burkitt lymphoma, drawn from the whole corpus: 5 items. Drugs are grouped by the most advanced trial phase they have reached anywhere; approved treatments sit under standard of care. Technologies are the methods being tested for this cancer, trials are the studies recorded here, and ideas are proposals not yet in a trial.
Relapsed Burkitt lymphoma is rarely curable; CD19-directed CAR-T and bispecifics are being tested.
Nothing recorded yet.
Nothing recorded yet.
Also on OnCo: Treatment journeys · Survivorship planner.
Cure rates in sub-Saharan Africa remain far below high-income countries; adapted protocols, rituximab access and supportive-care investment are the response.
Nothing recorded yet.
Also on OnCo: Financial help · Coverage by country · HTA decisions.
Acute toxicity (tumour lysis, mucositis, infection) of intensive regimens, particularly in adults and the immunocompromised.
Nothing recorded yet.
Nothing recorded yet.
Also on OnCo: Side effects by symptom · Immune-related side effects · Toxicity compare · Survivorship planner.
Late effects of anthracyclines and alkylators in survivors treated as children.
Nothing recorded yet.
Nothing recorded yet.
Also on OnCo: Side effects by symptom · Immune-related side effects · Toxicity compare · Survivorship planner.
Dated changes read from the records linked to this cancer: approvals, regulatory steps, reported trials, guideline versions and milestones. Newest first; no date is inferred.
On EdgeAll 10 changes by month →When this page itself was last checked or edited.
3-year EFS 93.
Minard-Colin and colleagues (NEJM 2020).
Schmitz and Richter (Nature, Nature Genetics) define the cooperating mutations.
Risk-stratified LMB or BFM regimen with intrathecal therapy; rituximab added for high-risk (stage III with high LDH, stage IV, leukaemic) disease per Inter-B-NHL Ritux 2010; low-intensity pre-phase and tumour lysis prophylaxis.
French SFOP protocol cures most children including stage IV.