What changed: Stage III melanoma (after surgery)
Every dated change on the records linked to Stage III melanoma (after surgery), newest first: approvals and regulatory steps on its medicines, trials that reported, guideline versions, milestones, and when this page itself was checked. Dates come from the records; none is inferred. Orientation, not medical advice.
Regulatory1Trial result7Milestone8This record1
September 2026 · 1
2026 · 2
2025 · 1
2024 · 2
2023 · 1
2022 · 2
2018 · 1
2017 · 4
- 2017Trial resultCheckMate 238CheckMate 238 reported
12-month recurrence-free survival 70.
- 2017Trial resultCOMBI-ADCOMBI-AD reported
10-year RFS 48% vs 32%; DMFS 63% vs 48%.
- 2017Trial resultMSLT-IIMSLT-II reported
No melanoma-specific survival benefit; lymphoedema 24% vs 6%.
- 2017MilestoneMSLT-IIMSLT-II: completion lymph node dissection abandoned; CheckMate 238 and COMBI-AD set adjuvant nivolumab and dabrafenib-trametinib
A milestone in how this cancer is treated.