Anbogen Therapeutics
Anbogen Therapeutics is a Taiwan-based biotechnology company that leads 2 cancer trials in OnCo, testing ABT-101 and ABT-301 in colorectal cancer and non-small-cell lung cancer.
Overview
Anbogen Therapeutics is a precision oncology company in Taipei developing targeted cancer therapies. Its candidates include ABT-101, licensed from Taiwan's National Health Research Institutes, and ABT-301, licensed from Taipei Medical University. On ClinicalTrials.gov it is the lead sponsor of 2 trials recorded in OnCo: NCT07244705 (phase 1/2, A Study of ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advance...) and NCT05532696 (phase 1/2, Phase 1b/2 Study to Evaluate ABT-101 in Solid Tumor and NSCLC Patients). Sponsor and trial facts are from the ClinicalTrials.gov registry; company facts are from the official website.
Scorecard
All companies- approved products +12
- phase 1/2 +1
- targets +6
- modalities +4
- regions +7
- 24-month regulatory events +6
- registry trials +30
ABT-301 is an experimental small-molecule drug from Anbogen Therapeutics in phase 2 trials for colorectal cancer, aimed at Histone deacetylases (HDAC).
A Chinese-developed PD-1 blocker, engineered to avoid a side-channel that may blunt other PD-1 drugs, now approved in the US and EU for oesophageal and stomach cancer.
Bevacizumab is a humanised antibody that soaks up VEGF-A, the signal tumours use to grow new blood vessels. Approved in 2004, it partners chemotherapy in colorectal, ovarian, cervical, lung, kidney and liver cancer and glioblastoma, and adds to trifluridine/tipiracil in late-line bowel cancer; hypertension, protein in the urine and bleeding are its characteristic side effects.
Similar pages
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Shares Tislelizumab, Colorectal cancer, Non-small-cell lung cancer.
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Shares Tislelizumab, Bevacizumab, Non-small-cell lung cancer.
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Shares Tislelizumab, Colorectal cancer.
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Shares Tislelizumab, Colorectal cancer, Non-small-cell lung cancer.
- TrialPhase III Study of SHR-8068 Combined With Adebrelimab and Chemotherapy Versus Tislelizumab Combined With Chemotherapy in the Treatment of Locally Adva
Shares Tislelizumab, Non-small-cell lung cancer.
- PersonJie Wang
Shares Tislelizumab, Non-small-cell lung cancer.
- TrialAK112 in Combination With Chemotherapy in Advanced Squamous Non-Small Cell Lung Cancer
Shares Tislelizumab, Non-small-cell lung cancer.
- TrialStudy of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer
Shares Bevacizumab, Colorectal cancer.