ABT-301
ABT-301 is an experimental small-molecule drug from Anbogen Therapeutics in phase 2 trials for colorectal cancer, aimed at Histone deacetylases (HDAC).
Overview
ABT-301 is a small-molecule drug developed by Anbogen Therapeutics. Its target is Histone deacetylases (HDAC). ClinicalTrials.gov describes the intervention as: ABT-301 is an oral histone deacetylase inhibitor (HDACi) administered in capsule form once daily (QD ±3 hours) or every 12 hours (Q12H ±3 hours, with at least 9 hours between doses) with water in 21-day treatment cycles. In Part 1 (dose-esc. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial, in colorectal cancer. The largest, NCT07244705, plans to enrol 66 participants with primary completion expected 2028-04. Status reflects the highest phase registered on ClinicalTrials.gov at the 2026-09-11 check; no efficacy results are recorded here.
Trials
topTrials recruiting now
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Latest papers
topQuery for this drug: (TITLE:"ABT-301" OR ABSTRACT:"ABT-301" OR TITLE:"MPT0E028" OR ABSTRACT:"MPT0E028" OR TITLE:"Imofinostat" OR ABSTRACT:"Imofinostat") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about ABT-301, not a curated reading list.
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