ABX-001 is an experimental arenavirus-based non-lytic viroimmunotherapy from Abalos Therapeutics, in phase 1 trials for advanced solid tumours.
ABX-001 is an arenavirus-based non-lytic viroimmunotherapy (intravenous) from Abalos Therapeutics. An arenavirus-based candidate given into a vein, designed to persist and replicate in cancer cells and antigen-presenting cells without destroying them, triggering innate and adaptive immune responses against the tumour. Its furthest stage is phase 1, for advanced solid tumours (refractory or relapsed). ClinicalTrials.gov registers it in one study linked below. First patient dosed 23 October 2025 (company release); NCT07231458 recruiting. Whether it works in people has not been established unless a trial below reports it.
An arenavirus-based candidate given into a vein, designed to persist and replicate in cancer cells and antigen-presenting cells without destroying them, triggering innate and adaptive immune responses against the tumour.
1.ABX-001 slips into a pocket on its target.
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Query for this drug: (TITLE:"ABX-001" OR ABSTRACT:"ABX-001") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about ABX-001, not a curated reading list.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
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