ADI-PEG20
ADI-PEG20 is an experimental investigational agent whose form is not stated in the registry from Polaris in phase 3 trials for hepatocellular carcinoma, with its target not yet stated publicly.
Overview
ADI-PEG20 (PEG20) is an investigational agent whose form is not stated in the registry developed by Polaris. Its molecular target is not stated in the ClinicalTrials.gov intervention record, and OnCo has not confirmed one from the sponsor's pipeline page. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial, including the phase 3 study NCT05317819 (Study of ADI-PEG 20 Versus Placebo in Subjects With High Arginine Level and Unresectable Hepatocellular Carcinoma), in hepatocellular carcinoma. The largest, NCT05317819, plans to enrol 300 participants with primary completion expected 2028-09. Status reflects the highest phase registered on ClinicalTrials.gov at the 2026-09-11 check; no efficacy results are recorded here.
Trials
topTrials recruiting now
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Landmark trials
Latest papers
topQuery for this drug: (TITLE:"ADI-PEG20" OR ABSTRACT:"ADI-PEG20" OR TITLE:"PEG20" OR ABSTRACT:"PEG20" OR TITLE:"pegargiminase" OR ABSTRACT:"pegargiminase") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about ADI-PEG20, not a curated reading list.
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